Salsa Baked Chicken- Skinless, Boneless Chicken Breasts Pace Salsa Directions: Preheat oven to 375 degrees, pour salsa over chicken and bake chicken for about 35 minutes or until there is no pink. Remove from oven. *Note you can also add some splenda brown sugar to the salsa, mix it well and pour on top. This is also a good mix. I would use roughy 1/4 of a cup though.